This short marks the debut appearance of Tootie, though here, she was voiced by Amber Hood, rather than Grey DeLisle, In this episode Tootie is already madly in love with Timmy. Tootie's glasses have round frames and she wears different clothing. Her pig-tails are shorter, and her hairline is different. Her pupils are blue instead of black.
Cosmo sneezed exactly 7 times in this episode, while Wanda sneezes 4 times.
This episode's title card is animated, showing a butterfly flying down the street before getting splattered on the windshield of a speeding truck.
Additionally, this is the first time an on-screen death is shown in the franchise (in this case, the butterfly being killed by a speeding truck.)
First episode where Timmy gets kissed by someone (Tootie, in this case).
This is the second episode with an animated title card.
When they played spin the bottle, Tootie said that the winner gets to kiss, her, but one of the player is a girl who seemed to not care if she won.
In addition to this being the debut episode of Tootie, this is also the first time we see Timmy with other kids which is a fairly rare occurrence in the Oh Yeah! Cartoon shorts.
This episode was aired on the same date as the first 3 pilot episodes of SpongeBob SquarePants.
Vicky calls Timmy "artichoke" in this episode.
Vicky's House is colored brown and yellow at first before turning green and white.
The clown is ridiculously tall in comparison to the rest of the house in some scenes.
In the very first episode, Vicky mentions she has a brother, but no other member of her family is mentioned or seen besides Tootie.
Most likely the brother was dropped and replaced with Tootie, as this was only referenced in the pilot episode.