This is the second Nicktoon to show a meteor heading towards Earth as a second extinction inspired by one being destroyed by the ages of the Dinosaurs. The first was "The Adventures of Jimmy Neutron: Boy Genius" shown in the episode: "Normal Boy".
Due to Timmy's wish, the rest of the episode only features music to tell characters emotions.
This is the first time Timmy saves Dimmsdale from a meteor from which he wished it gone.
This episode is inspired of what the world would be like without sound, as people would all use sign language to speak with their hands.
Lego - Locko is a parody of Lego, even the shapes of the blocks look similar.
Emergency Alert System - The test alert used by Chet Ubetcha to notify of a meteor threat is a parody of the Emergency Alert System, a system used in the United States on television and radio to viewers/listeners of national or local emergencies, which is tested weekly or monthly by television and radio broadcasters with a Required Weekly Test or a Required Monthly Test, respectively.
When someone hears about the meteor, they freak out and spit coffee (The Scientist, Wanda) and sometimes the coffee hits someone (Chet Ubetcha at the Scientist, Cosmo at Wanda twice, Cosmo at Timmy and Wanda)
Someone accidentally tipping Timmy's Eiffel tower made of blocks (Chet Ubetcha's meteor alarm, and Mr. Turner twice), except for Vicky, who did it on purpose.
Cosmo poofing up tacos during the charades sequence.
People not hearing themselves screaming.
People saying "Stop yelling at me".
Normally the characters in the Fairly OddParents have four fingers. However, when Timmy uses his hand to "charade" the word "for" it shows him with five fingers. while at the same time, his right hand has only four fingers as usual.
When Denzel Crocker saw Timmy with his fairies, they should have still been taken away. Although Mr. Crocker has seen Cosmo and Wanda before, it was explained in Information Stupor Highway that this is not a problem as long as Mr. Crocker doesn't know whose fairies Cosmo and Wanda are. In this episode, Mr. Crocker clearly sees Timmy alongside his fairies. However, it should be noted that since there is no sound, Crocker was able to see them, but he was unable to tell anybody that they are Timmy's fairies because in addition to everything being mute, everyone too busy running around panicking because of the meteor.